Teratogenic Effects of Trypan Blue on Hamster Embryos1

Teratogenic effects of trypan blue on hamster embryos.

L I T T L E information is available in the literature on the susceptibility of the hamster embryo to teratogens. Desoxycorticosterone acetate apparently has some teratogenic activity (Tedford & Risely, 1950), but the degree and type of abnormality produced by this agent in the hamster have not been recorded. Orsini (1952) has described naturally-occurring urogenital anomalies which appear in f...

Comparison of the different teratogenic effects of three commerical samples of trypan blue.

Comparison of the Different Teratogenic Effects of Three Commercial Samples of Trypan Blue

The Effects of Trypan Blue on Chick Embryos

VARIOUS malformations in rats and mice have been observed to be caused by administration of the vital dye, Trypan blue (Gillman, Gilbert, Gillman, & Spence, 1948; Fox & Goss, 1956, 1957; Hamburgh, 1952, 1954; Waddington & Carter, 1952, 1953). Recently Waddington & Perry (1956) reported a teratogenic effect of Trypan blue on Amphibian embryos. The present paper deals with the effects of this dye...

The preparation and teratogenic properties of pure trypan blue and its common contaminants.